Implementation of a disease trigger prediction model using AIML for early diagnosis of epilepsy

Epilepsy is one of the most prevalent neurological disorders that negatively impacts patients' quality of life and poses a severe health risk. It is often characterized by recurrent brain seizures. A current method that involves monitoring these seizures is Electroencephalography, which allows for the scientific investigation of electrical impulses within the brain. In this research, we have used Artificial Intelligence and Machine Learning in the management of Epilepsy to evaluate electrical impulses within the brain, emphasizing the potential to significantly improve the quality of life of those who suffer from this disorder. The goal of this study is to propose a Deep Neural Network model that can predict early seizure detection of Epilepsy using Electroencephalography data from a control group in order to anticipate the frequency of episodes of the patient and provide accurate insights into when they might experience their symptoms. Additionally, our research aims to identify particular genes of interest with specific protein targets that are directly responsible for the changes in EEG values in the epileptic patients. After thorough examination of these proteins' therapeutic targets and ligands, a suitable ligand and protein were identified and docked. The purpose of the docking studies in the Machine Learning model gains valuable information about the genetic origin for the change in EEG values in Epileptic patients. The integration of predictive modeling with in-silico drug discovery enhances both the diagnostic and therapeutic dimensions of epilepsy care. This dual-layered approach not only supports early warning systems but also opens avenues for personalized treatment strategies. Our study thus represents a step toward a more holistic, computationally driven framework for neurological disorder management. By bridging data-driven seizure prediction with molecular-level therapeutic exploration, this research contributes to precision medicine and highlights the potential of interdisciplinary computational approaches in tackling complex, treatment-resistant forms of epilepsy.

Authors

Institutions

Publication Details

Journal
Advances in Biomarker Sciences and Technology
Published
2025-01-01
DOI
https://doi.org/10.1016/j.abst.2025.07.001
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Implementation of a disease trigger prediction model using AIML for early diagnosis of epilepsy

Bhupendra Gopalbhai Prajapati, Shama Mujawar, Aarohi Gherkar, Shreyash Kolhe et al.
Advances in Biomarker Sciences and Technology
Epilepsy research and treatment
article

Implementation of a disease trigger prediction model using AIML for early diagnosis of epilepsy

Bhupendra Gopalbhai Prajapati, Shama Mujawar, Aarohi Gherkar, Shreyash Kolhe, Aarohi Deshpande, Avni Bhambure, Girish Shivhare
article en

Abstract

Epilepsy is one of the most prevalent neurological disorders that negatively impacts patients' quality of life and poses a severe health risk. It is often characterized by recurrent brain seizures. A current method that involves monitoring these seizures is Electroencephalography, which allows for the scientific investigation of electrical impulses within the brain. In this research, we have used Artificial Intelligence and Machine Learning in the management of Epilepsy to evaluate electrical impulses within the brain, emphasizing the potential to significantly improve the quality of life of those who suffer from this disorder. The goal of this study is to propose a Deep Neural Network model that can predict early seizure detection of Epilepsy using Electroencephalography data from a control group in order to anticipate the frequency of episodes of the patient and provide accurate insights into when they might experience their symptoms. Additionally, our research aims to identify particular genes of interest with specific protein targets that are directly responsible for the changes in EEG values in the epileptic patients. After thorough examination of these proteins' therapeutic targets and ligands, a suitable ligand and protein were identified and docked. The purpose of the docking studies in the Machine Learning model gains valuable information about the genetic origin for the change in EEG values in Epileptic patients. The integration of predictive modeling with in-silico drug discovery enhances both the diagnostic and therapeutic dimensions of epilepsy care. This dual-layered approach not only supports early warning systems but also opens avenues for personalized treatment strategies. Our study thus represents a step toward a more holistic, computationally driven framework for neurological disorder management. By bridging data-driven seizure prediction with molecular-level therapeutic exploration, this research contributes to precision medicine and highlights the potential of interdisciplinary computational approaches in tackling complex, treatment-resistant forms of epilepsy.

Advances in Biomarker Sciences and TechnologyVol. 7
MIT Art, Design and Technology University (IN), Ganpat University (IN), Chitkara University (IN)
Openalex Percentile: Top 79%
Epilepsy research and treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.