Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation
The present study elucidated the mechanism of quercetin, an active ingredient in TCM prescriptions, in the treatment of depression through data mining, network pharmacology prediction, and experimental validation. This integrated research method will provide a new perspective for the development of TCM.
Authors
- Zhujin Song
- Miaolian Wu
- Shasha Wu (ORCID: https://orcid.org/0000-0002-2461-6323)
- Guoqing Zhang (ORCID: https://orcid.org/0000-0001-8827-7546)
- Yuhua Wu
- Liping Luo (ORCID: https://orcid.org/0000-0003-2738-4908)
- Qingqing Hu (ORCID: https://orcid.org/0000-0002-9386-6481)
Institutions
- Zhejiang International Studies University (CN)
- Zhejiang Chinese Medical University (CN)
- Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3389/fnut.2025.1612746
- Citations
- 2
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- West China Hospital, Sichuan University