Analyzing the potential targets and mechanisms of liver damage induced by acetyl tributyl citrate plasticizer using network toxicology, molecular docking and in vitro experiments
The study suggests that TNF-α is involved in the process of ATBC-induced liver damage and may be related to cell apoptosis.
Authors
- Yueping Zeng (ORCID: https://orcid.org/0000-0002-7370-8187)
- Yun Fang (ORCID: https://orcid.org/0000-0001-9297-1514)
- Den Guo
- Zhendong Sun (ORCID: https://orcid.org/0000-0003-2134-6652)
- Jinwei Liang
- Ge Wang (ORCID: https://orcid.org/0000-0002-2656-7705)
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3389/fphar.2025.1636576
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province