Owner-Reported Clinical Outcomes of a Homeopathic Proprietary Preparation for the Treatment of Upper Respiratory and Nasal Disorders in Companion Animals

Background: Nasal and upper respiratory conditions are frequent issues in dogs and cats, presenting symptoms like sneezing, nasal obstruction, and various types of discharge. These can result from allergies, infections, foreign objects, or anatomical factors. While many cases respond to reatment, underlying issues often cause relapses. The investigational product offers apotential new approach for managing these nasal and sinus diseases in companion animals.Objectives: The primary objective of this PRO (Patient Reported Outcome) study was to assess the efficacy and safety HomeoPet® Nose Relief in Upper Respiratory Tract Disease Symptoms. Methods: This study was done on patient-reported outcome (PRO) data collected via an internet questionnaire. It is afacilitator-driven survey similar to previous studies17,18,19.Results: The study included 221 real-world patients split over four mall animal species, with dogs and cats being in the majority. Runny Nose 94 (44.76%), Sneezing 73 34.76%), Watery eyes 55 (26.19%), Nasal blockage 35 (16.67%), Upper respiratory infection 17 (8.1%), 6 (2.86%), Cold 30 (14.29%), Allergies 20 (9.52%), Nasal discharge 93 (44.29%) and Sinusitis 8 (11.94%) cases p< 0.0000001. In 61 (29.05%) pets, the symptoms were constant, while 71 (33.81%) had intermittent symptoms. The ANOVA revealed that there was an extremely weak downhill relationship between the pet type and efficacy of the medicine (p<0.0001). The analysis or correlation revealed a statistically significant, moderately high correlation between the frequency of symptoms and efficacy of Nose Relief in relieving the symptoms (R=0.408096, p<0.0001). Frequency of daily dose and age had a moderately low relationship with efficacy, in different directions. It can be administered orally-directly, in food, or water-with dosing 1 to 3 times daily generally sufficient. More frequent dosing was well tolerated and may be beneficial in acute or chronic nasal and upper respiratory conditions, offering a novel therapeutic option in veterinary care.Conclusion: Nose Relief, was found to be safe and effective for managing upper respiratory tract infections (URTIs) in companion animals.