Exploring the synergistic effects of Life’s Essential 8, insulin resistance, and CRP on cardiometabolic multimorbidity risk
Maintaining high LE8 scores is associated with a lower risk of developing CMM, partially mediated by reductions in IR and inflammation. Promoting CVH and addressing metabolic and inflammatory factors may help prevent CMM and reduce its burden on public health.
Authors
- Daidi Li
- Wenke Cheng
- Jiang Liu (ORCID: https://orcid.org/0000-0002-0654-707X)
- Chuang Yang (ORCID: https://orcid.org/0000-0003-2032-964X)
Institutions
- Humboldt-Universität zu Berlin (DE)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Yuxian People's Hospital (CN)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3389/fnut.2025.1598659
- Citations
- 2
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.78