Ellagic Acids and the Physiological Activities from the Twigs of Cercidiphyllum japonicum

3′-Di-O-methylellagic acid 4-O-β-D-glucopyranoside (1), 3,3′,4-tri-O-methylellagic acid (2), and methyl 4-hydroxy-benzoate (3) were isolated from the ethyl acetate fraction of the twigs of Cercidiphyllum japonicum, and their structures were confirmed by spectroscopic methods. These three compounds were found for the first time in C. japonicum. The ethyl acetate and butanol extracts of C. japonicum exhibited stronger DPPH scavenging activity than ascorbic acid, which was used as a positive control. and among the isolated compounds, compound 1 showed inhibition of elastin-degrading enzyme activity. Compound 2 showed the strongest DPPH radical scavenging activity, and significant inhibition of tyrosinase activity. The antibacterial activity of the solvent extracts was highest in the ethyl acetate extract.

Authors

Publication Details

Journal
Korean Journal of Pharmacognosy
Published
2025-06-30
DOI
https://doi.org/10.22889/kjp.2025.56.2.72
Primary Topic
Synthesis of Organic Compounds
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Ellagic Acids and the Physiological Activities from the Twigs of Cercidiphyllum japonicum

S Lee, Min-kyung Park
Korean Journal of Pharmacognosy
Synthesis of Organic Compounds
article

Ellagic Acids and the Physiological Activities from the Twigs of Cercidiphyllum japonicum

S Lee, Min-kyung Park
article en

Abstract

3′-Di-O-methylellagic acid 4-O-β-D-glucopyranoside (1), 3,3′,4-tri-O-methylellagic acid (2), and methyl 4-hydroxy-benzoate (3) were isolated from the ethyl acetate fraction of the twigs of Cercidiphyllum japonicum, and their structures were confirmed by spectroscopic methods. These three compounds were found for the first time in C. japonicum. The ethyl acetate and butanol extracts of C. japonicum exhibited stronger DPPH scavenging activity than ascorbic acid, which was used as a positive control. and among the isolated compounds, compound 1 showed inhibition of elastin-degrading enzyme activity. Compound 2 showed the strongest DPPH radical scavenging activity, and significant inhibition of tyrosinase activity. The antibacterial activity of the solvent extracts was highest in the ethyl acetate extract.

Korean Journal of PharmacognosyVol. 56(2)
Openalex Percentile: Top 80%
Synthesis of Organic Compounds
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.