Ellagic Acids and the Physiological Activities from the Twigs of Cercidiphyllum japonicum
3′-Di-O-methylellagic acid 4-O-β-D-glucopyranoside (1), 3,3′,4-tri-O-methylellagic acid (2), and methyl 4-hydroxy-benzoate (3) were isolated from the ethyl acetate fraction of the twigs of Cercidiphyllum japonicum, and their structures were confirmed by spectroscopic methods. These three compounds were found for the first time in C. japonicum. The ethyl acetate and butanol extracts of C. japonicum exhibited stronger DPPH scavenging activity than ascorbic acid, which was used as a positive control. and among the isolated compounds, compound 1 showed inhibition of elastin-degrading enzyme activity. Compound 2 showed the strongest DPPH radical scavenging activity, and significant inhibition of tyrosinase activity. The antibacterial activity of the solvent extracts was highest in the ethyl acetate extract.
Authors
- S Lee
- Min-kyung Park
Publication Details
- Journal
- Korean Journal of Pharmacognosy
- Published
- 2025-06-30
- DOI
- https://doi.org/10.22889/kjp.2025.56.2.72
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00