ULTRASTRUCTURAL MECHANISMS OF ADAPTATION OF THE OXYGEN TRANSPORT SYSTEM TO MUSCULAR WORK
stabilization in such cases presents a significant clinical challenge and often requires additional supportive strategies.Temporary mechanical circulatory support (MCS) has become an important component of modern CS management.Understanding the characteristics of each MCS device is crucial for their effective use in various clinical scenarios, which in turn contributes to improved medical care and increased patient survival.The aim of the study -to explore the current options for temporary mechanical circulatory support, compare their availability, advantages, and disadvantages based on contemporary literature, in order to optimize intensive therapy in patients with acute heart failure.We used bibliosemantic, comparative, and systems analysis methods.The results of this study are based on an analysis of current literature, randomized clinical trials, and meta-analyses focused on modern methods of temporary mechanical circulatory support.The use of MCS devices in patients with progressive heart failure who do not respond to conventional intensive care ensures hemodynamic support and stabilization and increases survival rates.Instead of perceiving these devices as competing technologies, it is important to understand each device individually in order to benefit from their unique properties in different clinical situations.Early use of MCS devices in CS is associated with better outcomes, as they reduce the negative impact of systemic hypoperfusion on target organs and the effects of inotropes/ vasopressors on oxygen consumption and myocardial microcirculation.
Authors
- H. V. Lukyantseva (ORCID: https://orcid.org/0000-0002-8054-0108)
- Sh.-A. S. Korman
Institutions
- National University of Ukraine on Physical Education and Sport (UA)
Publication Details
- Journal
- Bulletin of Problems Biology and Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.29254/2077-4214-2025-2-177-25-34
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00