Characterization of stem cell landscape and identification of stemness-related gene ENY2 in colorectal cancer by intergrated transcriptomic analysis

ENY2 may act as a key CSC-associated biomarker that promotes CRC tumorigenesis and metastasis via the EMT pathway, which enhance our understanding of CRC pathogenesis and highlight ENY2 as a potential target for diagnosis and therapy.

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Publication Details

Journal
Global Medical Genetics
Published
2025-07-16
DOI
https://doi.org/10.1016/j.gmg.2025.100067
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
0.00

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article

Characterization of stem cell landscape and identification of stemness-related gene ENY2 in colorectal cancer by intergrated transcriptomic analysis

Wende Hao, Zhenjun Wang, Huachong Ma
Global Medical Genetics
Cancer Cells and Metastasis
article

Characterization of stem cell landscape and identification of stemness-related gene ENY2 in colorectal cancer by intergrated transcriptomic analysis

Wende Hao, Zhenjun Wang, Huachong Ma
article en

Abstract

ENY2 may act as a key CSC-associated biomarker that promotes CRC tumorigenesis and metastasis via the EMT pathway, which enhance our understanding of CRC pathogenesis and highlight ENY2 as a potential target for diagnosis and therapy.

Global Medical GeneticsVol. 12(4)
Capital Medical University (CN), Beijing Chaoyang Emergency Medical Center (CN)
Wu Jieping Medical Foundation
Zero hunger
Openalex Percentile: Top 74%
Cancer Cells and Metastasis
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