Oxygen-Enhanced R2* Weighted MRI and Diffusion Weighted MRI of Head and Neck Squamous Cell Cancer Lymph Nodes in Prediction of 2-Year Outcome Following Chemoradiotherapy
This study demonstrates that a significant differential response to 100% oxygen and higher baseline R2* LN measurements could be exploited in risk stratification prior to CRT, and future work could be directed towards understanding the contrast mechanisms of R2* imaging, underpinning the observed differences in the context of hypoxia.
Authors
- Stuart A. Taylor (ORCID: https://orcid.org/0000-0002-6765-8806)
- M. Förster (ORCID: https://orcid.org/0000-0001-7639-290X)
- R. Mendes (ORCID: https://orcid.org/0000-0003-4754-1181)
- Sola Adeleke (ORCID: https://orcid.org/0000-0002-4388-8754)
- Shonit Punwani (ORCID: https://orcid.org/0000-0002-1014-0870)
- Tim Beale (ORCID: https://orcid.org/0000-0003-3312-1549)
- Harbir Sidhu (ORCID: https://orcid.org/0000-0003-3564-3383)
- Dawn Carnell (ORCID: https://orcid.org/0000-0002-2898-3219)
- David A. Price (ORCID: https://orcid.org/0000-0001-9416-2737)
- Simon Morley
- Marianthi‐Vasiliki Papoutsaki
Institutions
- University College Hospital (GB)
- University College London Hospitals NHS Foundation Trust (GB)
- CRUK Lung Cancer Centre of Excellence (GB)
- University College London (GB)
Publication Details
- Journal
- Cancers
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3390/cancers17142333
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00