CLINICAL CASE OF THE CLEAR CELL VARIANT OF PAPILLARY THYROID CARCINOMA

Contemporary medical literature indicates that metastases to the thyroid gland are relatively rare despite its rich vascular supply, accounting for approximately 1–3% of all malignant thyroid tumors. However, autopsy series studies demonstrate that metastases in the thyroid gland can be found in up to 24% of patients with advanced malignant disease.Objective. To examine a clinical case of a patient with papillary thyroid carcinoma.A clinical case was reviewed: Patient M., 75 years old, presented with a multinodular goiter.Results and Discussion: At the time of presentation, thyroid hormone levels were consistent with a euthyroid state. The patient complained of the presence of thyroid nodules and a sensation of discomfort. His medical history included previous surgical interventions: 25 years ago – left nephrectomy and splenectomy due to a renal neoplasm (discharge summaries not available); 10 years ago – prostatectomy and orchiectomy due to a malignant prostate tumor (no documentation provided). Laboratory parameters were within normal limits.Based on the medical history, physical examination, and ultrasound findings, a diagnosis of multinodular euthyroid goiter was established.A planned thyroidectomy was performed. No suspicion of malignancy was raised either prior to or during the surgical procedure.Histological Conclusion: Clear cell variant of papillary thyroid carcinoma.Oncologist's Conclusion: The treatment was carried out according to a radical protocol, and radioiodine therapy is not indicated for this patient. Replacement therapy with Euthyrox 100 mcg was prescribed.At follow-up visits, the patient's condition was satisfactory, with no complaints reported.Conclusion: Although metastases to the thyroid gland are rare, they should be considered in patients with a history of malignant tumors, particularly renal cell carcinoma.