PERSONALIZED APPROACH TO THE TREATMENT OF ENDOCRINE ORBITOPATHY BASED ON A DIGITAL PROTOCOL AND EVALUATION OF ITS CLINICAL EFFECTIVENESS

Endocrine orbitopathy (EO) is one of the most common complicaons of Graves' disease and is characterised by inammatory and broc changes in the orbital structures.Tradional approaches to surgical treatment do not always take into account the individual anatomical features of paents, which limits clinical eecveness and can lead to complicaons.The aim of the study was to evaluate the clinical ecacy of a personalised approach to surgical treatment of EO based on a digital protocol that includes virtual planning, volumetry and the manufacture of navigaon surgical templates (NSTs).A prospecve cohort study was conducted, which included 35 paents with EO, divided into a main group (using a personalised approach, computer modelling methods, and surgical naviga-on templates) and a control group (tradional technique).All paents underwent mulspiral CT with subsequent 3D modelling and stracaon of the disease form.The main criteria for evaluang eecveness were indicators of exophthalmos, lagophthalmos, diplopia, and hypoesthesia.Both methods provided a signicant reducon in exophthalmos and lagophthalmos.The personalised approach demonstrated a considerable reducon in diplopia (p=0.027) and the frequency of hypoesthesia (p=0.014), which are the main complicaons of orbital decompression.The use of a personalised digital protocol in the treatment of EO provides higher clinical ecacy, a reducon in the frequency of complicaons and an improvement in the quality of life of paents, conrming the feasibility of its im-plementaon in clinical pracce.