Critically Important Cancer Outcomes to Report in Kidney Transplant Trials

The Standardized Outcomes in Nephrology-Transplantation (SONG-Tx) international consensus process, involving patients, caregivers and health professionals, identified cancer as a core outcome for kidney transplant trials1. Transplant recipients experience a 2-3-fold increased risk of cancer and cancer death compared to their age- and sex-matched peers2,3. The increased risk of cancer is largely attributed to the effects of long-term immunosuppression, which impairs immune surveillance and immunity to oncogenic viruses4.

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Publication Details

Journal
Kidney International Reports
Published
2025-07-16
DOI
https://doi.org/10.1016/j.ekir.2025.07.006
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Critically Important Cancer Outcomes to Report in Kidney Transplant Trials

Bianca Davidson, Kenar D. Jhaveri, Alejandra Mena‐Gutierrez, Curie Ahn et al.
Kidney International Reports
Renal Transplantation Outcomes and Treatments
article

Critically Important Cancer Outcomes to Report in Kidney Transplant Trials

Bianca Davidson, Kenar D. Jhaveri, Alejandra Mena‐Gutierrez, Curie Ahn, Kenneth A. Newell, Hélio Tedesco‐Silva, Jonathan C. Craig, Armando Teixeira‐Pinto, Ellen Dobrijevic, Nicole Jane Scholes-Robertson, Germaine Wong, Christopher D. Blosser, Sergio A. Acuña, Anna Francis, Amy Von Huben, Martin Howell, Anita van Zwieten, Naoka Murakami, Jolanta Małyszko, Allison Jaure
article en

Abstract

The Standardized Outcomes in Nephrology-Transplantation (SONG-Tx) international consensus process, involving patients, caregivers and health professionals, identified cancer as a core outcome for kidney transplant trials1. Transplant recipients experience a 2-3-fold increased risk of cancer and cancer death compared to their age- and sex-matched peers2,3. The increased risk of cancer is largely attributed to the effects of long-term immunosuppression, which impairs immune surveillance and immunity to oncogenic viruses4.

Kidney International ReportsVol. 10(10)
Seattle Children's Hospital (US), The University of Sydney (AU), Seoul National University (KR), Emory University (US), University of Cape Town (ZA), Flinders University (AU), University of Washington (US), Washington University in St. Louis (US), Medical University of Warsaw (PL), Groote Schuur Hospital (ZA), Children's Hospital at Westmead (AU), Westmead Hospital (AU), UNSW Sydney (AU), University of Alabama at Birmingham (US), Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US), Children's Health Queensland Hospital and Health Service (AU), Wake Forest University (US), Universidade Federal de São Paulo (BR)
National Health and Medical Research Council
Good health and well-being
Openalex Percentile: Top 79%
Renal Transplantation Outcomes and Treatments
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