In vitro Study of the Effects of Acetylcysteine on the International Normalized Ratio Over Time
This in vitro study showed a clinically significant effect of increasing acetylcysteine concentrations on INR over time at 37°C in pooled plasma. Additionally, a large interindividual variability was observed.
Authors
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Marieke G. G. Sturkenboom (ORCID: https://orcid.org/0000-0002-3420-0591)
- Jenny E. Kootstra‐Ros (ORCID: https://orcid.org/0000-0002-1394-513X)
- Messia Nazar
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1097/ftd.0000000000001356
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00