Multi-voxel pattern analysis for characterizing functional connectivity and neurocognitive function in major depression: A CAN-BIND-1 report
Our findings highlight that MDD is associated with disrupted rsFC across networks relevant to neurocognitive function. The data-driven nature of the fc-MVPA identified the left cerebellar crus I as the most significant region of aberrant rsFC.
Authors
- Fatemeh Gholamali Nezhad
- Stephen C. Strother (ORCID: https://orcid.org/0000-0002-3198-217X)
- Nathan W. Churchill (ORCID: https://orcid.org/0000-0001-8481-2505)
- Tom A. Schweizer (ORCID: https://orcid.org/0000-0003-2278-3539)
- Roumen Milev (ORCID: https://orcid.org/0000-0001-6884-171X)
- Sidney H. Kennedy (ORCID: https://orcid.org/0000-0001-5339-7185)
- Alice Rueda (ORCID: https://orcid.org/0000-0002-9977-9653)
- V. Peters
- Venkat Bhat (ORCID: https://orcid.org/0000-0002-8768-1173)
- Benicio Noronha Frey (ORCID: https://orcid.org/0000-0001-8267-943X)
- Stefanie Hassel (ORCID: https://orcid.org/0000-0001-7240-1581)
- Valerie H. Taylor (ORCID: https://orcid.org/0000-0002-8948-638X)
- Vanessa K. Tassone (ORCID: https://orcid.org/0000-0002-9208-8809)
- Ilya Demchenko (ORCID: https://orcid.org/0000-0001-7876-4981)
- Raymond W. Lam (ORCID: https://orcid.org/0000-0001-7142-4669)
- Sheeba Arnold Anteraper
- Daniel J. Müller (ORCID: https://orcid.org/0000-0003-4978-4400)
Institutions
- St. Michael's Hospital (CA)
- TRIUMF (CA)
- Centre for Addiction and Mental Health (CA)
- University of British Columbia (CA)
- University of Calgary (CA)
- Kingston General Hospital (CA)
- Baycrest Hospital (CA)
- St Michael’s Hospital (IE)
- Advanced Imaging Research (United States) (US)
- St. Joseph’s Healthcare Hamilton (CA)
Publication Details
- Journal
- NeuroImage Clinical
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.nicl.2025.103840
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00