Rare variant genetic landscape of familial chylomicronemia syndrome (FCS) in the United Kingdom
The genetic architecture of FCS in the United Kingdom is complex, with a substantial proportion affected by non-<i>LPL</i> FCS-causing genes. It also displays a significant regional and ethnic variations.
Authors
- Handrean Soran (ORCID: https://orcid.org/0000-0003-1714-5014)
- Natalie Forrester (ORCID: https://orcid.org/0000-0003-0033-7423)
- Jaimini Cegla (ORCID: https://orcid.org/0000-0003-1168-0366)
- Yee Teoh
- Robert A. Hegele (ORCID: https://orcid.org/0000-0003-2861-5325)
- Michael Mansfield (ORCID: https://orcid.org/0000-0002-1044-3935)
- Maryam Ferdousi
- Bilal Bashir (ORCID: https://orcid.org/0000-0003-3733-8331)
- Hannah Delaney
- Jonathan Schofield (ORCID: https://orcid.org/0000-0001-6030-993X)
- Sarah Marsh
- Charlotte Dawson (ORCID: https://orcid.org/0000-0002-9621-6468)
- Anthony S. Wierzbicki (ORCID: https://orcid.org/0000-0003-2756-372X)
- Pankaj Gupta (ORCID: https://orcid.org/0000-0001-9481-6067)
- D. Datta (ORCID: https://orcid.org/0000-0001-7856-7363)
- Ahai Luvai (ORCID: https://orcid.org/0000-0001-8508-2209)
- Anoushka Kamath (ORCID: https://orcid.org/0009-0000-0235-4695)
- Paul Hamilton (ORCID: https://orcid.org/0000-0001-6437-9185)
- Paul N. Durrington (ORCID: https://orcid.org/0000-0001-9561-7887)
- Paul Downie
- Jian Wang (ORCID: https://orcid.org/0009-0005-2983-0993)
- C. E. Dent
- Dawn O’Sullivan
- Fiona Jenkinson
- Deanna Mamood
Institutions
- Western University (CA)
- Queen's University Belfast (GB)
- North Bristol NHS Trust (GB)
- University Hospitals Birmingham NHS Foundation Trust (GB)
- St Thomas' Hospital (GB)
- University of Aberdeen (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- Wrexham Maelor Hospital (GB)
- Royal Victoria Infirmary (GB)
- University Hospitals of Leicester NHS Trust (GB)
- Bristol Royal Infirmary (GB)
- University of Manchester (GB)
- Manchester University NHS Foundation Trust (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- St. Thomas Hospital (CA)
- University Hospital Llandough (GB)
- Imperial College London (GB)
- University of Sulaimani (IQ)
Publication Details
- Journal
- Genetics in Medicine Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.gimo.2025.103445
- Citations
- 1
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Institute for Health and Care Research
- Manchester Biomedical Research Centre