Fibroblast activation protein-expression in colorectal carcinomas and implications for clinical application
CRCs and LN metastases generally express FAP, but levels vary significantly between and within tumours and have no direct correlation with TSR. Care has to be taken translating FAPI-PET/CT results with e.g. disease extent and activity, emphasizing the importance of multidisciplinary approach.
Authors
- Meaghan Polack (ORCID: https://orcid.org/0000-0001-7980-7533)
- Gabi W. van Pelt (ORCID: https://orcid.org/0000-0003-1449-7348)
- J. Han van Krieken (ORCID: https://orcid.org/0000-0002-8105-0450)
- Rob A.�E.�M. Tollenaar (ORCID: https://orcid.org/0000-0002-6831-6082)
- Stijn Crobach (ORCID: https://orcid.org/0000-0002-1289-4406)
- Lioe‐Fee de Geus‐Oei (ORCID: https://orcid.org/0000-0003-1817-2743)
- Wilma E. Mesker (ORCID: https://orcid.org/0000-0001-5533-4778)
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- University of Twente (NL)
- Delft University of Technology (NL)
Publication Details
- Journal
- Cancer Treatment and Research Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.ctarc.2025.100964
- Citations
- 1
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.05