High-Resolution Genotyping of HLA Alleles and Association with Genetic Background of Virological Response in Chronic Hepatitis B

Integrating next-generation sequencing data of HLA genes in genomic and epigenomic data can offer a comprehensive understanding of the molecular mechanisms underlying HBV infection. This integrated approach will help identify new biomarkers, deeply understand the complex interactions between genetic and epigenetic factors, and facilitate the development of personalized prevention and treatment strategies.