Molecular, Clinical Features, and Prognostic Implications of PTPN11 Mutation in Adult Patients with Acute Myeloid Leukemia in China

This study highlights the molecular and clinical heterogeneity of PTPN11 mutations in AML, emphasizing their prognostic complexity and the need for integrated molecular profiling. These findings provide valuable insights into the role of PTPN11 mutations and underscore the importance of personalized treatment approaches based on genetic risk stratification.

Authors

Publication Details

Journal
Clinical Laboratory
Published
2025-01-01
DOI
https://doi.org/10.7754/clin.lab.2025.241242
Primary Topic
Acute Myeloid Leukemia Research
Type
article
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article

Molecular, Clinical Features, and Prognostic Implications of PTPN11 Mutation in Adult Patients with Acute Myeloid Leukemia in China

Lingrong He, Hongjuan Yu
Clinical Laboratory
Acute Myeloid Leukemia Research
article

Molecular, Clinical Features, and Prognostic Implications of PTPN11 Mutation in Adult Patients with Acute Myeloid Leukemia in China

Lingrong He, Hongjuan Yu
article en

Abstract

This study highlights the molecular and clinical heterogeneity of PTPN11 mutations in AML, emphasizing their prognostic complexity and the need for integrated molecular profiling. These findings provide valuable insights into the role of PTPN11 mutations and underscore the importance of personalized treatment approaches based on genetic risk stratification.

Clinical LaboratoryVol. 71(07/2025)
Good health and well-being
Openalex Percentile: Top 78%
Acute Myeloid Leukemia Research
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Molecular, Clinical Features, and Prognostic Implications of PTPN11 Mutation in Adult Patients with Acute Myeloid Leukemia in China — Lingrong He, Hongjuan Yu · Clinical Laboratory (2025) | TGRS Research Map | TGRS