Genetic Variants in Pediatric Myeloproliferative Neoplasms Revealed by Next Generation Sequencing

The results suggest a different genetic profile in pediatric MPN, with a lower incidence of driver variants in pediatric ET and multiple non-driver variants with poor prognostic implications in pediatric PMF.

Authors

Publication Details

Journal
Clinical Laboratory
Published
2025-01-01
DOI
https://doi.org/10.7754/clin.lab.2025.250321
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
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article

Genetic Variants in Pediatric Myeloproliferative Neoplasms Revealed by Next Generation Sequencing

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Myeloproliferative Neoplasms: Diagnosis and Treatment
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Genetic Variants in Pediatric Myeloproliferative Neoplasms Revealed by Next Generation Sequencing

Heyjin Kim, Chang‐Hun Park, Ki-O Lee, Jae Sung Yun, Keun‐Young Yoo, Boram Kim, Hee‐Jin Kim, Hyun‐Young Kim
article en

Abstract

The results suggest a different genetic profile in pediatric MPN, with a lower incidence of driver variants in pediatric ET and multiple non-driver variants with poor prognostic implications in pediatric PMF.

Clinical LaboratoryVol. 71(07/2025)
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Myeloproliferative Neoplasms: Diagnosis and Treatment
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