Clinical case of toxic epidermal necrolysis (Lyell's syndrome) in pediatric practice

A clinical case of toxic epidermal necrolysis (TEN) in a pediatric patient is presented as a severe pathological process occurring with widespread skin lesions and erosive lesions of the mucous membranes. TEN develops more often as an allergic reaction in response to drugs, the triggers maybe pathogens of infectious diseases. A drug-induced disease may occur in the practice of a pediatrician. To improve the prognosis, timely diagnosis and the use of an individual treatment protocol are important. The presented clinical case confirms the importance of timely diagnosis and early initiation of individual therapy.

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Publication Details

Journal
Siberian Journal of Clinical and Experimental Medicine
Published
2025-07-13
DOI
https://doi.org/10.29001/2073-8552-2025-40-2-176-182
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Clinical case of toxic epidermal necrolysis (Lyell's syndrome) in pediatric practice

О. В. Кириченко, G.D. Alemanova, L.Yu. Popova, E. I. Pogrebnova
Siberian Journal of Clinical and Experimental Medicine
Drug-Induced Adverse Reactions
article

Clinical case of toxic epidermal necrolysis (Lyell's syndrome) in pediatric practice

О. В. Кириченко, G.D. Alemanova, L.Yu. Popova, E. I. Pogrebnova
article en

Abstract

A clinical case of toxic epidermal necrolysis (TEN) in a pediatric patient is presented as a severe pathological process occurring with widespread skin lesions and erosive lesions of the mucous membranes. TEN develops more often as an allergic reaction in response to drugs, the triggers maybe pathogens of infectious diseases. A drug-induced disease may occur in the practice of a pediatrician. To improve the prognosis, timely diagnosis and the use of an individual treatment protocol are important. The presented clinical case confirms the importance of timely diagnosis and early initiation of individual therapy.

Siberian Journal of Clinical and Experimental MedicineVol. 40(2)
Orenburg State Medical Academy (RU), Regional Children's Clinical Hospital No. 1 (RU)
Openalex Percentile: Top 80%
Drug-Induced Adverse Reactions
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