Evaluating the effects of bempedoic acid on lipid profiles and cardiovascular risk: An umbrella review of meta-analyses

Our findings show that bempedoic acid significantly reduces the risk of MACE, nonfatal MI, coronary and noncoronary revascularization, and hospitalizations for unstable angina. While results on cardiovascular mortality are mixed, suggesting a need for further study, bempedoic acid proves to be an effective treatment for improving lipid profiles and reducing cardiovascular events, especially in patients who cannot tolerate statins. It presents a valuable option for cardiovascular risk management, potentially enhancing patient outcomes and quality of life. Further research is needed to assess its long-term benefits and broader applicability.

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Publication Details

Journal
Qatar medical journal
Published
2025-06-30
DOI
https://doi.org/10.5339/qmj.2025.51
Citations
1
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
2.01
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article

Evaluating the effects of bempedoic acid on lipid profiles and cardiovascular risk: An umbrella review of meta-analyses

Anim Asif, Umair Baig, Aatkah Naseer, Owais Ali et al.
1 citations
Qatar medical journal
Lipoproteins and Cardiovascular Health
2.01
article

Evaluating the effects of bempedoic acid on lipid profiles and cardiovascular risk: An umbrella review of meta-analyses

Anim Asif, Umair Baig, Aatkah Naseer, Owais Ali, Sheena Shamoon, Rubaid Azhar Dhillon, Palak Patel, Sameer Bhimani, Vikash Kumar Karmani, Adina Amir, Shahzeb Saeed, Ashik Ali
article en
1 citations

Abstract

Our findings show that bempedoic acid significantly reduces the risk of MACE, nonfatal MI, coronary and noncoronary revascularization, and hospitalizations for unstable angina. While results on cardiovascular mortality are mixed, suggesting a need for further study, bempedoic acid proves to be an effective treatment for improving lipid profiles and reducing cardiovascular events, especially in patients who cannot tolerate statins. It presents a valuable option for cardiovascular risk management, potentially enhancing patient outcomes and quality of life. Further research is needed to assess its long-term benefits and broader applicability.

Qatar medical journalVol. 2025(2)
Charleston Area Medical Center (US), Rawalpindi Medical University (PK), New York Medical College (US), Riphah International University (PK), Sindh Institute of Urology and Transplantation (PK), Karachi Institute of Heart Diseases (PK), Jinnah Sindh Medical University (PK), Harlem Hospital Center (US), Dow University of Health Sciences (PK), SRM Dental College (IN), The Wright Center for Graduate Medical Education (US), SRM University (IN), National Institute of Cardiovascular Diseases (PK), Saint Michael's Medical Center (US), Pakistan Institute of Medical Sciences (PK)
Good health and well-being
Openalex Percentile: Top 14%
Lipoproteins and Cardiovascular Health
2.01
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