Methanol leaf extract of <i>Azadirachta</i> <i>indica</i> mitigates isoproterenol-induced myocardial infarction through the modulation of oxidative stress, and PPARα and BCL2 signaling in rats.
Mitigation of oxidative mechanisms and antihypertensive effects of <i>Azadirachta indica</i> suggest a positive modulatory role for the medicinal plant in isoproterenol-induced myocardial infarction.
Authors
- Temitayo Olabisi Ajibade (ORCID: https://orcid.org/0000-0003-1971-8621)
- Temidayo Olutayo Omóbòwálé (ORCID: https://orcid.org/0000-0002-9486-2861)
- Amirah Folashade Yusuf (ORCID: https://orcid.org/0000-0003-2755-4698)
- Joseph Ayotunde Badejo
- Oluwaseun Olanrewaju Esan (ORCID: https://orcid.org/0000-0002-9933-876X)
- Adeolu Alex Adedapo (ORCID: https://orcid.org/0000-0003-3003-7579)
- Ademola Adetokunbo Oyagbemi (ORCID: https://orcid.org/0000-0002-8996-8610)
- Momoh Audu Yakubu (ORCID: https://orcid.org/0000-0002-6072-2473)
- Oluwafemi Omoniyi Oguntibeju (ORCID: https://orcid.org/0000-0002-7299-1128)
- Matthew O. Akpan
- Moyinoluwa Julianah Onoja (ORCID: https://orcid.org/0009-0000-2509-9439)
- Racheal Ebunoluwa Asenuga
Institutions
- Cape Peninsula University of Technology (ZA)
- University of Ibadan (NG)
- Texas Southern University (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ajp.2024.25277
- Primary Topic
- Botanical Research and Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00