Immunological Correlation in Different Cutaneous Clinical Types of Lupus Erythematosus in the Bulgarian Population.
Our data confirmed the strong association between anti-dsDNA, anti-Sm, anti-Sm/RNP and SLE, as well as anti-SSA/Ro 52 and anti-SSA/Ro 60 and subacute cutaneous LE. ANA is a relevant marker of lupus disease activity. All lupus patients with ANA higher than 320 titter had a bad disease control. Based on our results, ANA and anti-SSB/La could be used as follow-up markers for a disease conversion form CLE to SLE. Anti-SSB/La antibodies are found in higher prevalence in patients with discoid cutaneous LE.
Authors
- V. Ouzounova-Raykova (ORCID: https://orcid.org/0000-0002-9199-9600)
- Lyubomir Dourmishev (ORCID: https://orcid.org/0000-0001-8458-1241)
- Dimitrina Guleva (ORCID: https://orcid.org/0000-0002-4350-3287)
- L. Miteva
Institutions
- Medical University of Sofia (BG)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00