Clinical application of chitosan-based biopolymer wound dressing in the treatment of a patient with lymphoma and extensive chronic wounds

The aim of the study is to analyze the existing scientific data on the use of chitosan-based wound dressings and their effectiveness, as well as to present our own experience with the use of chitosan-based polymer coatings in the treatment of chronic wounds in a lymphoma patient in the purulent surgery department. Material and methods. A clinical case of a 69-year-old patient with recurrent B-cell lymphoma, initially treated in the hematology department, and subsequently transferred to the purulent surgery department due to the development of necrotizing fasciitis, is presented. Chitosan-based polymer dressings were used for the healing of a large chronic skin defect that developed after necrosectomy. Dressings were applied for 20 days in the hospital and for 30 days in the outpatient setting. Results. The application of chitosan-based polymer dressings showed significant positive dynamics: the wound began to epithelialize, which was accompanied by an improvement in the patient’s overall condition and compensation of comorbidities during the treatment. As a result, significant progress was made in restoring the patient’s functional activity, and they weredischarged with the ability to move independently. At the 6-month follow-up, complete wound healing was noted. Conclusions. The analysis of the existing literature and our own experience with chitosan-based biopolymer dressings demonstrated their effectiveness in the treatment of chronic wounds in patients with severe comorbidities. This method represents a promising trend in the surgical treatment of such patients.