COPPER OXIDE CATALYZED AMIDES FROM OXIDATIVE AMIDATION OF BENZYL AMINE, STYRENE, AND PHENYL ACETIC ACIDS WITH DMF AS AMINE SOURCE

Hydrothermal-assisted Copper oxide (CuO) nanocatalyst, which is found to be an efficient heterogeneous catalyst for the synthesis of amides through oxidative amidation of benzyl amine, styrene, and phenyl acetic acid with DMF as an amine source, respectively. The prepared CuO was further investigated using XRD, FTIR, and TEM which resulting monoclinic structure with a 27 nm was formed without impurities. Various substituted benzyl amines, styrenes, phenyl acetic acids, and formamides are well amidation and afforded the various N, N-substituted benzamides in moderate to good yields. The synthesized CuO nanocatalyst showed high reactivity with significant reusability for the synthesis of amides.