Theoretical Mechanism and Scientific Basis of Fire-Acupuncture “Taixi” Point in the Treatment of Cold-Fear Syndrome with Yang Deficiency

怕冷症是以机体能量代谢障碍、产热不足为核心，表现为持续畏寒且难以缓解的病理状态。本文基于中医“温肾助阳”理论，以足少阴肾经的原穴太溪为干预靶点，系统整合火针疗法的经典理论、现代作用机制及临床实践证据，探讨其治疗怕冷症的多维作用路径。理论层面，立足中医古籍与传统中医理论，阐释火针、太溪穴通过激活肾阳、贯通三焦气机的温煦机制；机制层面，揭示火针通过瞬时高温(600℃~800℃)刺激触发“热膨胀效应–神经内分泌调节–微循环重建”的级联反应，涉及下丘脑–垂体–肾上腺/甲状腺轴功能调控，为火针太溪穴治疗阳虚型怕冷症的方案优化提供科学依据，凸显传统外治法在现代慢病管理中的转化价值。Cold-fear syndrome is a pathological state centered on impaired energy metabolism and insufficient heat production, which is characterized by persistent cold-fear syndrome and is difficult to relieve. Based on the theory of “warming the kidney and promoting yang” in traditional Chinese medicine, this paper takes Taixi, the original point of the foot-shao yin kidney meridian, as the target point of intervention, and systematically integrates the classical theory, modern mechanism of action, and evidence of clinical practice of fire-acupuncture therapy, to explore the multidimensional pathway of its treatment of frigidity. At the theoretical level, based on the ancient Chinese medical books and traditional Chinese medical theories, we explain the warming mechanism of fire acupuncture and Taixi by activating the kidney yang and penetrating the Sanjiao qi; at the mechanistic level, it is revealed that fire acupuncture triggers the cascade reaction of “thermal expansion effect-neuroendocrine regulation-microcirculation reconstruction” through the stimulation of instantaneous high temperature (600˚C~800˚C), which involves the functional regulation of hypothalamus-pituitary-adrenal/thyroid axis, providing a scientific basis for the optimization of the protocol for the treatment of cold-fear syndrome with Yang deficiency by fire-acupuncture on Taixi point, and highlighting the translational value of the traditional external therapeutic method in the modern management of chronic diseases.