Rare presentation of cervical choriocarcinoma with metastasis: a case report

Background: Choriocarcinoma of the cervix is an extremely rare sporadic disease with an incidence of 0.76 to 4%. This malignant form of gestational trophoblastic disease typically originates in the uterus but can occasionally arise in the vagina, fallopian tubes, vulva, cervix or pelvic region. Case: Our patient presented with heavy menstrual bleeding and elevated B-Human Chorionic Gonadotropin (B-HCG) levels. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH + BSO). Histopathological diagnosis confirmed choriocarcinoma and a post-surgery Computed Tomography (CT) scan revealed lung metastasis. Treatment usually involves combination chemotherapy, which is highly effective, with cure rates reaching 100% in low-risk patients and 80–90% in high-risk patients. Conclusions: This report highlights the importance of a meticulous, multidisciplinary approach in managing patients who present with choriocarcinoma at unusual sites like cervix that can easily be missed and misdiagnosed.