Aquasomes: A Novel Nanoparticulate Drug Delivery System for Psoriasis Treatment

New nanoparticulate carriers called aquasomes are applied topically to administer drugs, especially in dermatology. These carriers consist of a solid core, often made of calcium phosphate or ceramic, covered by a polyhydroxy oligomer layer. This unique shape protects the bioactivity of fragile molecules like proteins, enzymes, and genetic material. Aquasomes are particularly helpful for enhancing the regulated release, stability, and bioavailability of medicinal substances while lowering systemic absorption and undesirable side effects. Skin conditions are among the most prevalent health issues in the world and have a significant financial burden. The psychological, social, and financial effects of skin diseases on patients, their families, and society as a whole are all included in the multifaceted concept of the burden of skin diseases. While malignant diseases like malignant melanoma carry a high death rate, chronic and incurable skin conditions like psoriasis and eczema are linked to severe morbidity in the form of physical discomfort and a reduction in patients' quality of life. Treatment ideas have significantly evolved as a result of psoriasis, a systemic disorder with distinctive skin signs and related conditions. The intricacy of psoriasis necessitates not only the right treatment but also weight-loss and smoking cessation programs, as well as the removal of trigger factors. 1. Improved medication delivery; 2. Better skin penetration; 3. Anti-inflammatory benefits; 4. Skin barrier repair and moisturization; and 5. Decreased drug resistance and adverse effects are some of its mechanisms