Assessing Acute and Long‐Term Toxicities of Proton Radiation Therapy in Pediatric Pelvic Tumors: Findings From the Pediatric Proton Consortium Registry
Our findings demonstrate the safety profile of PT among pediatric patients while identifying specific risk factors, such as passive scattering proton therapy and abdominal irradiation, that contribute to increased GI toxicity. While proton therapy appears to be a well-tolerated treatment option, the observed toxicity rates highlight the need for continued monitoring and long-term follow-up.
Authors
- Patricio C. Gargollo (ORCID: https://orcid.org/0000-0001-9512-5946)
- Arnold C. Paulino (ORCID: https://orcid.org/0000-0002-0269-3045)
- Ralph P. Ermoian (ORCID: https://orcid.org/0000-0002-7514-0943)
- Torunn Ingrid Yock (ORCID: https://orcid.org/0000-0001-6408-8011)
- Christine E. Hill‐Kayser (ORCID: https://orcid.org/0000-0002-1993-1185)
- J. Chang (ORCID: https://orcid.org/0000-0002-2059-6599)
- Stephen A. Mihalcik (ORCID: https://orcid.org/0000-0003-2145-467X)
- Young Kwok (ORCID: https://orcid.org/0000-0003-1484-8507)
- Jamil Almohtasib (ORCID: https://orcid.org/0000-0002-5055-674X)
- Daniel J. Indelicato (ORCID: https://orcid.org/0000-0001-5765-1873)
- Nadia N. Laack (ORCID: https://orcid.org/0000-0002-4385-6349)
- John Peter Perentesis (ORCID: https://orcid.org/0000-0002-4237-8226)
- Wael Zeina
- Jae Young Lee (ORCID: https://orcid.org/0000-0003-4493-2494)
- Stephanie M. Perkins
Institutions
- University of North Florida (US)
- University of Maryland, Baltimore (US)
- Cincinnati Children's Hospital Medical Center (US)
- University of Maryland Medical Center (US)
- Mayo Clinic (US)
- The University of Texas MD Anderson Cancer Center (US)
- Harvard University (US)
- University of Washington (US)
- Washington University in St. Louis (US)
- University of Florida (US)
- Jacksonville University (US)
- Massachusetts General Hospital (US)
- Northwestern Medicine (US)
- ProCure (United States) (US)
- University of Oklahoma Health Sciences Center (US)
- University of Pennsylvania (US)
- Florida College (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1002/pbc.31811
- Citations
- 2
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01