Metal- and base-free spirocyclization of alkylidene oxindoles <i>via</i> photo- and mechanochemically-generated nitrile ylides and nitrile imines as 1,3-dipoles
We report an efficient, metal- and base-free synthesis of spiro[pyrrolidine-3,3′-oxindoles] and spiro[indoline-3,3′-pyrazol]-2-ones via 3 + 2 cycloadditions of in situ generated nitrile ylides and nitrile imines with alkylidene oxindoles.
Authors
- Rakesh Ganguly (ORCID: https://orcid.org/0000-0002-9523-6918)
- Subhabrata Sen (ORCID: https://orcid.org/0000-0002-4608-5498)
- Mahesh Kumar Ravva (ORCID: https://orcid.org/0000-0001-9619-0176)
- R. Pandey (ORCID: https://orcid.org/0000-0003-0398-9566)
- Shweta Singh (ORCID: https://orcid.org/0009-0006-0372-3628)
- Varun Christopher
Institutions
- Shiv Nadar University (IN)
- SRM University (IN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00851d
- Citations
- 1
- Primary Topic
- Advanced Synthetic Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.94