Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire

Objective This study aimed to assess whether a statistically significant correlation exists between socioeconomic status, measured by the Index of Multiple Deprivation (IMD), and the incidence of head and neck cancer (HNC) in Greater Manchester and East Cheshire. Understanding this relationship can help inform targeted public health interventions and reduce healthcare disparities. Methods Using Multidisciplinary Team (MDT) lists, 236 HNC patients from Manchester University NHS Foundation Trust were identified. Patient demographics and residential postcodes were extracted from the HIVE electronic patient record system. Postcodes were then mapped to IMD deciles using the UK Government's official postcode-to-IMD lookup tool. This allowed for the categorisation of patients by area-level socioeconomic deprivation. Results The analysis revealed a negative correlation (ρ = -0.21) between socioeconomic status, as indicated by IMD decile, and the incidence of HNC cases. Statistical analysis showed that this correlation was not statistically significant at the α = 0.05 level. Conclusion While this study did not identify a statistically significant correlation between socioeconomic deprivation and HNC incidence, a weak negative trend was observed. These exploratory findings suggest potential geographic and socioeconomic patterns that warrant further investigation. Understanding these trends may support more targeted public health strategies - especially in regions with a higher disease burden - and contribute to efforts aimed at earlier diagnosis and improved health outcomes.

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Publication Details

Journal
Cureus
Published
2025-07-14
DOI
https://doi.org/10.7759/cureus.87936
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire

Mahesh C. Yadav, Niketa Chotai, Danuksha K Amarasena, Rohit Kumar
Cureus
Head and Neck Cancer Studies
article

Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire

Mahesh C. Yadav, Niketa Chotai, Danuksha K Amarasena, Rohit Kumar
article en

Abstract

Objective This study aimed to assess whether a statistically significant correlation exists between socioeconomic status, measured by the Index of Multiple Deprivation (IMD), and the incidence of head and neck cancer (HNC) in Greater Manchester and East Cheshire. Understanding this relationship can help inform targeted public health interventions and reduce healthcare disparities. Methods Using Multidisciplinary Team (MDT) lists, 236 HNC patients from Manchester University NHS Foundation Trust were identified. Patient demographics and residential postcodes were extracted from the HIVE electronic patient record system. Postcodes were then mapped to IMD deciles using the UK Government's official postcode-to-IMD lookup tool. This allowed for the categorisation of patients by area-level socioeconomic deprivation. Results The analysis revealed a negative correlation (ρ = -0.21) between socioeconomic status, as indicated by IMD decile, and the incidence of HNC cases. Statistical analysis showed that this correlation was not statistically significant at the α = 0.05 level. Conclusion While this study did not identify a statistically significant correlation between socioeconomic deprivation and HNC incidence, a weak negative trend was observed. These exploratory findings suggest potential geographic and socioeconomic patterns that warrant further investigation. Understanding these trends may support more targeted public health strategies - especially in regions with a higher disease burden - and contribute to efforts aimed at earlier diagnosis and improved health outcomes.

CureusVol. 17(7)
University Hospitals of North Midlands NHS Trust (GB), Dudley Group NHS Foundation Trust (GB), University Hospitals of Leicester NHS Trust (GB), University of Manchester (GB), Manchester University NHS Foundation Trust (GB), Manchester University (US)
Good health and well-being
Openalex Percentile: Top 76%
Head and Neck Cancer Studies
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