The Effect of Perioperative Pregabalin Administration in Postoperative Pain Control After Laminectomy and Instrumented Fusion in Degenerative Lumbar Spine Disease
Preoperative doses of 150 mg or 300 mg of pregabalin did not significantly alter opioid consumption or its side effects compared with a placebo. However, a notable reduction in pain was observed 24 hours postsurgery in the pregabalin groups.
Authors
- Monchai Ruangchainikom (ORCID: https://orcid.org/0000-0003-0525-6390)
- Vimolluck Sanansilp
- Nantthasorn Zinboonyahgoon (ORCID: https://orcid.org/0000-0002-5946-7962)
- Panya Luksanapruksa (ORCID: https://orcid.org/0000-0002-9554-4259)
- Sirichai Wilartratsami (ORCID: https://orcid.org/0000-0001-7651-4196)
- Borriwat Santipas (ORCID: https://orcid.org/0000-0001-6804-6644)
Institutions
- Siriraj Hospital (TH)
- Mahidol University (TH)
Publication Details
- Journal
- Clinical Spine Surgery A Spine Publication
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1097/bsd.0000000000001832
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00