P-16 Secondary glaucoma treatment and graft failure in penetrating keratoplasty for advanced acanthamoeba keratitis: 5 years follow-up

1.5% Acanthamoeba spp.There were significant differences in the microbiological profiles and in vitro drug susceptibilities between West and East Kent regions.The most common organisms were Pseudomonas spp (46%) in West Kent and Staphylococcus spp (32%) in East Kent.There was decreased sensitivity of fluoroquinolones to pseudomonas spp over the time period.Conclusion Microbial keratitis in Kent shares some similarities to other regions within the UK.There are some regional differences in the frequency of organisms.Antimicrobial resistance to fluoroquinolones was observed so therapy selection for empirical treatment should be based on local isolate analysis.