Management of Human Papillomavirus Associated Oral Lesions with Topical Acyclovir: Two Case Report

The purpose of this paper is to present the findings on the effective topical treatment of HPV-associated lesions using topical Zovirax. Two patients presented with HPV related lesions discovered on routine examination. The findings indicate that this topical antiviral treatment is effective, non-invasive, and cost-efficient, while also posing a lower risk over a reasonable duration compared to other therapeutic options. There has been only one prior report documenting the use of 1% cidofovir gel on gingival lesions in an HIV-positive individual, and the first report concerning Heck's disease. This approach is of significance especially in immunocompromised or those with polypharmacy.