A scRNA-seq reference contrasting living and early post-mortem human retina across diverse donor states
Our atlas provides a single-cell reference contrasting living versus early postmortem human retina, integrating cell type composition, transcriptional diversity, and functional insights. It may serve as a useful resource for retinal research and for understanding aspects of human retinal biology, particularly given its inclusion of living tissue and diverse pathological states.
Authors
- Luning Yang (ORCID: https://orcid.org/0000-0001-9056-5950)
- Richard Rankin (ORCID: https://orcid.org/0000-0001-6445-2602)
- Yongqing Shao (ORCID: https://orcid.org/0009-0006-1319-8521)
- Weihua Meng (ORCID: https://orcid.org/0000-0001-5388-8494)
- Tengda Cai (ORCID: https://orcid.org/0000-0003-1617-506X)
- Gareth J. McKay (ORCID: https://orcid.org/0000-0001-8197-6280)
- Quanyong Yi (ORCID: https://orcid.org/0000-0002-9369-3998)
- Zen Huat Lu (ORCID: https://orcid.org/0000-0002-9408-0579)
- Yiwen Tao (ORCID: https://orcid.org/0009-0000-0102-4205)
- Yunyan Ye (ORCID: https://orcid.org/0009-0005-2325-1405)
- Yang Zhou (ORCID: https://orcid.org/0000-0001-9273-0489)
- Jianhui Liu (ORCID: https://orcid.org/0009-0004-1341-0831)
- Lie Chen (ORCID: https://orcid.org/0000-0001-9764-4299)
- Qi Pan (ORCID: https://orcid.org/0000-0003-0135-9122)
Institutions
- Ningbo University (CN)
- Queen's University Belfast (GB)
- University of Nottingham Ningbo China (CN)
- University of Dundee (GB)
- Universiti Brunei Darussalam (BN)
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s40246-025-00796-9
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81