Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia

LSGS-induced repolarization shortening is absent in ischaemic myocardium. RSGS was more arrhythmogenic following CX occlusion than LSGS or control. These data demonstrate that the arrhythmogenic influence of RSGS or LSGS is contingent on the location of ischaemic zone supporting the clinical findings that bilateral sympathectomy is superior to left sympathectomy alone.

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Publication Details

Journal
Cardiovascular Research
Published
2025-07-14
DOI
https://doi.org/10.1093/cvr/cvaf121
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
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article

Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia

Ruben Coronel, Bastiaan J. Boukens, Veronique M.F. Meijborg, Kalyanam Shivkumar et al.
Cardiovascular Research
Cardiac Arrhythmias and Treatments
article

Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia

Ruben Coronel, Bastiaan J. Boukens, Veronique M.F. Meijborg, Kalyanam Shivkumar, Ronald Challita, Al-Hassan Dajani, Joseph Hadaya, Jeffrey L. Ardell, Steven Cha, Michiel J. Janse
article en

Abstract

LSGS-induced repolarization shortening is absent in ischaemic myocardium. RSGS was more arrhythmogenic following CX occlusion than LSGS or control. These data demonstrate that the arrhythmogenic influence of RSGS or LSGS is contingent on the location of ischaemic zone supporting the clinical findings that bilateral sympathectomy is superior to left sympathectomy alone.

Cardiovascular ResearchVol. 121(9)
Utrecht University (NL), Heidelberg University (DE), University of Massachusetts Amherst (US), UCLA Health (US), Leiden University Medical Center (NL), Maastricht University Medical Centre (NL), University Hospital Heidelberg (DE), University Medical Center Utrecht (NL), Maastricht University (NL), Texas Cardiac Arrhythmia (US), University of Amsterdam (NL)
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Openalex Percentile: Top 72%
Cardiac Arrhythmias and Treatments
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Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia — Ruben Coronel, Bastiaan J. Boukens, et al. · Cardiovascular Research (2025) | TGRS Research Map | TGRS