Adaptation Follow Human Attention: Gaze-Assisted Medical Segment Anything Model

Segment Anything Model (SAM) has demonstrated state-of-the-art performance in most segmentation tasks. However, due to insufficient training in the medical domain, SAM’s ability to generalize to medical images is limited. Although preliminary efforts have fine-tuned SAM for the medical domain, the fine-tuned model still struggles with variability in medical tasks. Some recent studies have explored weakly supervised learning to mitigate SAM’s performance degradation in the medical domain. However, the effectiveness of weakly supervised learning is heavily dependent on the quality of weakly supervised information, with performance significantly dropping as the quality declines. Doctors’ attention is closely related to the target area during diagnosis. Integrating gaze information into SAM’s adaptation process for medical image segmentation enhances efficiency and significantly improves performance in medical tasks. In this paper, we first propose a Gaze-assisted medical segment Anything Model (GAM), which utilizes gaze information to enable the adaptation of SAM in medical images following doctor’s attention. It has two innovations: 1) Feature-level adaptation: Gaze Alignment (GA) learning makes the feature-level adaptation follow the doctor’s attention which mines the human guidance from gaze heatmaps and guides model to extract general features for downstream tasks. 2) Output-level adaptation: Gaze-Balance (GB) learning makes the output-level adaptation follow the doctor’s attention which utilizes gaze heatmaps to enhance the human-focused area and solve the problem of over/under segmentation from the output-level. Our promising results on 7 tasks with 12 targets have demonstrated the powerful adaptation ability of our GAM in the medical domain. Our GAM demonstrates significant potential for low-cost clinical assistance in medical diagnosis, enabling SAM to adapt to the medical image domain without disrupting clinical workflows. We have released the full source code on https://github.com/Ruiz1026/GAM.