<i>t</i>-BuOK-Induced, NH₃·MeOH-Promoted Electrochemical C(sp³)–H Amination of Saturated Heterocycles with Sulfoximines

The <i>t</i>-BuOK-induced electrochemical C(sp³)-H amination of saturated heterocycles with sulfoximines was reported. <i>t</i>-BuOK rather than dangerous peroxides was used as the precursor of the <i>tert</i>-butoxy radical, which was induced by electrochemistry; this process has not been previously reported. Notably, we found that NH₃·MeOH can serve as a promoter in electrochemical oxidation reactions. This C-H/N-H cross-dehydrogenation coupling reaction produces only the green byproduct H₂ and has the advantages of atom economy, lack of transition metals, lack of external oxidants, and mild reaction conditions.