Determination of Salivary CD44 as a Noninvasive Diagnostic Biomarker to Predict Malignant Transformation of Oral Submucous Fibrosis

Our study was the first of its kind to assess the expression of CD44 in OSMF patients. Results infer that CD44 may decrease with the progression of normal mucosa to OSMF and with different grades, however, future studies are required with larger sample size to determine CD44 as molecular biomarker.

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Publication Details

Journal
Contemporary Clinical Dentistry
Published
2025-04-01
DOI
https://doi.org/10.4103/ccd.ccd_37_25
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Determination of Salivary CD44 as a Noninvasive Diagnostic Biomarker to Predict Malignant Transformation of Oral Submucous Fibrosis

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Determination of Salivary CD44 as a Noninvasive Diagnostic Biomarker to Predict Malignant Transformation of Oral Submucous Fibrosis

Sukanya Ravindran, Nalini Aswath, Vijayalakshmi Ramshankar, Rajalakshmi Rakshanaa, K. Mehanathan
article en

Abstract

Our study was the first of its kind to assess the expression of CD44 in OSMF patients. Results infer that CD44 may decrease with the progression of normal mucosa to OSMF and with different grades, however, future studies are required with larger sample size to determine CD44 as molecular biomarker.

Contemporary Clinical DentistryVol. 16(2)
Cancer Institute (WIA) (IN), Sree Balaji Dental College and Hospital (IN), Bharath University (IN)
Good health and well-being
Openalex Percentile: Top 81%
Oral Health Pathology and Treatment
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