IGF2BP1 promotes the progression of head and neck squamous cell carcinoma by activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition
Our findings demonstrate that IGF2BP1 plays a critical role in promoting HNSCC growth and metastasis, highlighting its potential as a therapeutic target.
Authors
- Yanshi Li
- Mengna Wang (ORCID: https://orcid.org/0000-0002-6903-8854)
- Zhaobo Cheng (ORCID: https://orcid.org/0000-0002-0600-3208)
- Min Pan (ORCID: https://orcid.org/0000-0002-8419-9357)
- R. Liu
- Lin Chen (ORCID: https://orcid.org/0000-0003-2237-8568)
- Guohua Hu (ORCID: https://orcid.org/0000-0002-9550-2534)
- Tao Lü (ORCID: https://orcid.org/0000-0002-0931-1257)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s12957-025-03929-5
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Chongqing Medical University