Pd-Catalyzed C–H Functionalization/Annulation of 2-Aryl-1,3-dicarbonyls with Vinylcyclopropanes: Merging C–H and C–C Activation

Pd-catalyzed enol-directed cascade C-H functionalization and annulation of 2-aryl-1,3-dicarbonyls have been developed using vinylcyclopropanes as a coupling partner. Utilization of an intrinsic weak chelating group, C-C/C-O bond formation, substrate scope, functional group tolerance, subsequent hydrogenolysis, and hydrogenation of products to furnish alkylated 2-aryl-1,3-dicarbonyls and late-stage product modifications are the important practical features.