Irisin regulates cardiac myocyte energy metabolic remodeling involved the ADRA1A-AMPK signaling pathwayng pathway
Irisin showcases substantial therapeutic potential against hypoxia-induced cardiomyocyte damage, acting predominantly through the AMPK signaling pathway. Its efficacy in enhancing cardiac function and energy metabolism in vivo further underscores its promise as a prospective treatment for cardiac conditions characterized by hypoxia.
Authors
- Jing Li (ORCID: https://orcid.org/0000-0001-8669-4901)
- Bei Yuan
- Feng Gao (ORCID: https://orcid.org/0000-0003-0618-2047)
- Zhe Han (ORCID: https://orcid.org/0000-0002-3822-2317)
- Qingliang Chen (ORCID: https://orcid.org/0009-0007-2466-3334)
Institutions
- Tianjin University (CN)
- Affiliated Hospital of Hebei University (CN)
- Tianjin Chest Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s40001-025-02882-z
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16