Royal jelly alleviates gemcitabine-induced ovarian toxicity: an investigation on rat models
RJ partially reduced inflammatory response and oxidative stress, supported follicular development, increased AMH expression, and alleviated histopathological damage. This original study highlights the potential of RJ as a natural adjunct to preserve ovarian reserve during gemcitabine chemotherapy, while emphasizing the need for further research to determine its long-term effects and optimal dosage.
Authors
- Kübra Tuğçe Kalkan (ORCID: https://orcid.org/0000-0001-7461-277X)
- Demet Bolat (ORCID: https://orcid.org/0000-0002-3496-1630)
- Betül Yalçın (ORCID: https://orcid.org/0000-0002-5533-330X)
- Halil Yıldız (ORCID: https://orcid.org/0000-0003-3103-1638)
- Ertan Katırcı (ORCID: https://orcid.org/0000-0002-3781-9162)
- Eda Köseoğlu (ORCID: https://orcid.org/0000-0002-0502-7814)
- Arzu Yay (ORCID: https://orcid.org/0000-0001-8532-3543)
Institutions
- Ahi Evran University (TR)
- Department of Embryology (US)
- Erciyes University (TR)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s12906-025-05013-7
- Citations
- 2
- Primary Topic
- Bee Products Chemical Analysis
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- Ahi Evran Üniversitesi