Impact of Preoperative Conjunctival Vascular Area on Surgical Outcomes in Trabeculectomy with Mitomycin C for Glaucoma: A Comprehensive Analysis

Trabeculectomy with mitomycin C is a key surgical intervention for managing glaucoma when conservative treatments fail. The success of trabeculectomy is influenced by various factors, including preoperative ocular characteristics like conjunctival vascularity. This study aims to explore the relationship between the preoperative conjunctival vascular area and post-trabeculectomy outcomes in glaucoma patients. By analyzing the conjunctival vascular density, intraocular pressure (IOP), bleb morphology, laser suture lysis (LSL) frequency, and postoperative eye drops, this research sheds light on the impact of preoperative vascularity on surgical success. Results show that lower preoperative conjunctival vessel density is associated with favorable outcomes, such as better bleb formation and reduced need for postoperative interventions, while higher conjunctival vessel density correlates with complications like hyphema. These findings emphasize the importance of assessing preoperative conjunctival vascularity to optimize trabeculectomy outcomes and personalize treatment strategies for glaucoma patients.

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Journal
Vision
Published
2025-07-14
DOI
https://doi.org/10.3390/vision9030058
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

Impact of Preoperative Conjunctival Vascular Area on Surgical Outcomes in Trabeculectomy with Mitomycin C for Glaucoma: A Comprehensive Analysis

Takayuki Inada, Y. Hayakawa
Vision
Glaucoma and retinal disorders
article

Impact of Preoperative Conjunctival Vascular Area on Surgical Outcomes in Trabeculectomy with Mitomycin C for Glaucoma: A Comprehensive Analysis

Takayuki Inada, Y. Hayakawa
article en

Abstract

Trabeculectomy with mitomycin C is a key surgical intervention for managing glaucoma when conservative treatments fail. The success of trabeculectomy is influenced by various factors, including preoperative ocular characteristics like conjunctival vascularity. This study aims to explore the relationship between the preoperative conjunctival vascular area and post-trabeculectomy outcomes in glaucoma patients. By analyzing the conjunctival vascular density, intraocular pressure (IOP), bleb morphology, laser suture lysis (LSL) frequency, and postoperative eye drops, this research sheds light on the impact of preoperative vascularity on surgical success. Results show that lower preoperative conjunctival vessel density is associated with favorable outcomes, such as better bleb formation and reduced need for postoperative interventions, while higher conjunctival vessel density correlates with complications like hyphema. These findings emphasize the importance of assessing preoperative conjunctival vascularity to optimize trabeculectomy outcomes and personalize treatment strategies for glaucoma patients.

VisionVol. 9(3)
Urawa University (JP), Saitama Prefectural Kumagaya Girls High School (JP), Kawagoe Technical High School (JP), Kisarazu Hospital (JP), Dokkyo Medical University Saitama Medical Center (JP)
Good health and well-being
Openalex Percentile: Top 74%
Glaucoma and retinal disorders
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Impact of Preoperative Conjunctival Vascular Area on Surgical Outcomes in Trabeculectomy with Mitomycin C for Glaucoma: A Comprehensive Analysis — Takayuki Inada, Y. Hayakawa · Vision (2025) | TGRS Research Map | TGRS