Postoperative complications prognosis optimization in patients with breast cancer
Breast cancer remains one of the widespread diseases in female population. Surgical method is the basic approach to cytoreduction at the early stage of disease diagnostics, ensuring the achievement of higher rates of distant relapse-free and overall survival. However, surgical complications remain an acute concern. Performing preserving surgeries with biopsy of the sentinel lymph node in the postoperative period can lead to the development of hematoma, seroma, infection, and flap necrosis. The developed method of breast resection with lymph node dissection significantly reduced early postoperative complications by 3.8% (against 27.6% with standard incision, p < 0.05). Inflammatory infiltrate in the postoperative wound area occurred in 1.9% of patients (compared to 11.4% with the standard incision, p < 0.05), and seroma in the postoperative wound area occurred in 1.9% of patients (compared to 14.2% with the standard incision, p < 0.05). We successfully tested our proposed method for predicting early postoperative complications, and it showed prognostic value. The main predictor of the onset of wound complications was the index of microcirculation. Thermometry was an additional method. Thus, the use of Z-shaped incision for breast cancer preserving surgery, as well as the use of screening techniques, is important for prognosis optimization of early surgical complications.
Authors
- L. A. Trusova (ORCID: https://orcid.org/0000-0002-6438-685X)
- S. A. Stolyarov
Publication Details
- Journal
- Vestnik SurGU Meditsina
- Published
- 2025-01-01
- DOI
- https://doi.org/10.35266/2949-3447-2025-2-7
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00