Postoperative complications prognosis optimization in patients with breast cancer

Breast cancer remains one of the widespread diseases in female population. Surgical method is the basic approach to cytoreduction at the early stage of disease diagnostics, ensuring the achievement of higher rates of distant relapse-free and overall survival. However, surgical complications remain an acute concern. Performing preserving surgeries with biopsy of the sentinel lymph node in the postoperative period can lead to the development of hematoma, seroma, infection, and flap necrosis. The developed method of breast resection with lymph node dissection significantly reduced early postoperative complications by 3.8% (against 27.6% with standard incision, p < 0.05). Inflammatory infiltrate in the postoperative wound area occurred in 1.9% of patients (compared to 11.4% with the standard incision, p < 0.05), and seroma in the postoperative wound area occurred in 1.9% of patients (compared to 14.2% with the standard incision, p < 0.05). We successfully tested our proposed method for predicting early postoperative complications, and it showed prognostic value. The main predictor of the onset of wound complications was the index of microcirculation. Thermometry was an additional method. Thus, the use of Z-shaped incision for breast cancer preserving surgery, as well as the use of screening techniques, is important for prognosis optimization of early surgical complications.

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Publication Details

Journal
Vestnik SurGU Meditsina
Published
2025-01-01
DOI
https://doi.org/10.35266/2949-3447-2025-2-7
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Postoperative complications prognosis optimization in patients with breast cancer

L. A. Trusova, S. A. Stolyarov
Vestnik SurGU Meditsina
Breast Cancer Treatment Studies
article

Postoperative complications prognosis optimization in patients with breast cancer

L. A. Trusova, S. A. Stolyarov
article en

Abstract

Breast cancer remains one of the widespread diseases in female population. Surgical method is the basic approach to cytoreduction at the early stage of disease diagnostics, ensuring the achievement of higher rates of distant relapse-free and overall survival. However, surgical complications remain an acute concern. Performing preserving surgeries with biopsy of the sentinel lymph node in the postoperative period can lead to the development of hematoma, seroma, infection, and flap necrosis. The developed method of breast resection with lymph node dissection significantly reduced early postoperative complications by 3.8% (against 27.6% with standard incision, p < 0.05). Inflammatory infiltrate in the postoperative wound area occurred in 1.9% of patients (compared to 11.4% with the standard incision, p < 0.05), and seroma in the postoperative wound area occurred in 1.9% of patients (compared to 14.2% with the standard incision, p < 0.05). We successfully tested our proposed method for predicting early postoperative complications, and it showed prognostic value. The main predictor of the onset of wound complications was the index of microcirculation. Thermometry was an additional method. Thus, the use of Z-shaped incision for breast cancer preserving surgery, as well as the use of screening techniques, is important for prognosis optimization of early surgical complications.

Vestnik SurGU MeditsinaVol. 18(2)
Openalex Percentile: Top 77%
Breast Cancer Treatment Studies
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