Blood-Epigenetic Biomarker Associations with Tumor Immunophenotype in Patients with Urothelial Carcinoma from JAVELIN Bladder 100
Our findings suggest that polygenic host factors may affect response to ICIs and support further investigation of chromatin conformation assays.
Authors
- Janusz Dutkowski
- Shibing Deng (ORCID: https://orcid.org/0000-0002-2867-263X)
- Jie Pu
- Matthew Salter (ORCID: https://orcid.org/0009-0009-1159-7213)
- Cora Nanette Sternberg (ORCID: https://orcid.org/0000-0003-3938-2627)
- Robbin Nameki (ORCID: https://orcid.org/0000-0002-2538-5694)
- Keith A. Ching (ORCID: https://orcid.org/0009-0000-9575-0039)
- Robert A. Amezquita (ORCID: https://orcid.org/0000-0001-6868-7193)
- Petros D. Grivas (ORCID: https://orcid.org/0000-0003-3965-3394)
- Alessandra di Pietro (ORCID: https://orcid.org/0009-0009-1887-6610)
- Diane R. Fernandez (ORCID: https://orcid.org/0000-0003-1365-5172)
- Srikala S. Sridhar (ORCID: https://orcid.org/0000-0002-6994-1285)
- Roy Ronen
- Jayne Green
- Alexandre Akoulitchev
- Craig B. Davis (ORCID: https://orcid.org/0000-0002-1703-451X)
- Ann Dring
- Thomas Powles
- Michelle Saul (ORCID: https://orcid.org/0000-0002-6991-3217)
- Ryan Powell
- Ewan Hunter (ORCID: https://orcid.org/0000-0003-1754-2685)
- Chao-Hui Huang (ORCID: https://orcid.org/0000-0002-3837-8135)
- Joaquim Bellmunt
Institutions
- St Bartholomew's Hospital (GB)
- Harvard University (US)
- Queen Mary University of London (GB)
- Pfizer (United States) (US)
- University of Toronto (CA)
- University of Washington (US)
- Cornell University (US)
- Princess Margaret Cancer Centre (CA)
- Lander Institute (IL)
- Fred Hutch Cancer Center (US)
- Dana-Farber Cancer Institute (US)
- Pfizer (Italy) (IT)
- Education Development Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3390/cancers17142332
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer