Comparative Evaluation of Flaxseed (Linum usitatissimum) and Ferrous Sulphate in Tannic Acid-Induced Iron Deficiency Anaemia in Wistar Rats

This study assessed the hematinic effect of Linum usitatissimum (flaxseed) on iron-deficiency anaemia in Albino Wistar rats. Anemia was induced using tannic acid, and the rats were divided into five groups for 30 days. Group one received a standard diet, group two a standard diet with ferrous sulphate and the remaining groups received a standard diet with different concentrations of flaxseed extract. Hematological parameters, including hemoglobin, MCV, MCHC, and MCH levels, were measured before and after treatment. The results showed that flaxseed extract showed dose-dependent improvement in hematological parameters, compared to ferrous sulphate, suggesting its potential as a natural treatment for iron-deficiency anaemia. Higher doses of flaxseed extract may further enhance the therapeutic benefits in patients with iron-deficiency anemia.

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Publication Details

Journal
Biomedical & Pharmacology Journal
Published
2025-06-30
DOI
https://doi.org/10.13005/bpj/3200
Primary Topic
Iron Metabolism and Disorders
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article
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article

Comparative Evaluation of Flaxseed (Linum usitatissimum) and Ferrous Sulphate in Tannic Acid-Induced Iron Deficiency Anaemia in Wistar Rats

Sougata Sarkar, Vartika Srivastava, Sumit Sethi, Chaitali Pattnayak et al.
Biomedical & Pharmacology Journal
Iron Metabolism and Disorders
article

Comparative Evaluation of Flaxseed (Linum usitatissimum) and Ferrous Sulphate in Tannic Acid-Induced Iron Deficiency Anaemia in Wistar Rats

Sougata Sarkar, Vartika Srivastava, Sumit Sethi, Chaitali Pattnayak, Suman Supreeti
article en

Abstract

This study assessed the hematinic effect of Linum usitatissimum (flaxseed) on iron-deficiency anaemia in Albino Wistar rats. Anemia was induced using tannic acid, and the rats were divided into five groups for 30 days. Group one received a standard diet, group two a standard diet with ferrous sulphate and the remaining groups received a standard diet with different concentrations of flaxseed extract. Hematological parameters, including hemoglobin, MCV, MCHC, and MCH levels, were measured before and after treatment. The results showed that flaxseed extract showed dose-dependent improvement in hematological parameters, compared to ferrous sulphate, suggesting its potential as a natural treatment for iron-deficiency anaemia. Higher doses of flaxseed extract may further enhance the therapeutic benefits in patients with iron-deficiency anemia.

Biomedical & Pharmacology JournalVol. 18(2)
Institute of Medical Sciences (IN), KIIT University (IN), Maulana Abul Kalam Azad University of Technology, West Bengal (IN)
Openalex Percentile: Top 79%
Iron Metabolism and Disorders
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Comparative Evaluation of Flaxseed (Linum usitatissimum) and Ferrous Sulphate in Tannic Acid-Induced Iron Deficiency Anaemia in Wistar Rats — Sougata Sarkar, Vartika Srivastava, et al. · Biomedical & Pharmacology Journal (2025) | TGRS Research Map | TGRS