Case Report: Persistent drug-resistant Pseudomonas aeruginosa infection in a young post-kidney transplant patient that proved fatal

This case report highlights the management of recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) <i>Pseudomonas aeruginosa</i> in a post-renal transplant patient. Despite the challenges posed by antibiotic resistance, the patient was successfully treated with an extended infusion of meropenem, underscoring the efficacy of this approach in such difficult cases. The patient's recurrent infections required multiple hospitalizations and adjustments in treatment protocols, including the use of alternative antibiotics like fosfomycin and tailored immunosuppressive management to control both infection and rejection. This case is noteworthy for demonstrating the successful management of recurrent UTIs in the immunocompromised patient population, providing valuable insights into the treatment strategies that can be employed in similar clinical scenarios.

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Publication Details

Journal
Frontiers in Transplantation
Published
2025-07-14
DOI
https://doi.org/10.3389/frtra.2025.1500066
Citations
1
Primary Topic
Urinary Tract Infections Management
Type
article
Field-Weighted Citation Impact
1.35

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article

Case Report: Persistent drug-resistant Pseudomonas aeruginosa infection in a young post-kidney transplant patient that proved fatal

Ramakota Reddy, G. K. Megha, Manjunath S Shetty, Gautam Kalyatanda et al.
1 citations
Frontiers in Transplantation
Urinary Tract Infections Management
1.35
article

Case Report: Persistent drug-resistant Pseudomonas aeruginosa infection in a young post-kidney transplant patient that proved fatal

Ramakota Reddy, G. K. Megha, Manjunath S Shetty, Gautam Kalyatanda, Asha Srinivasan, Yogeesh D. Maheshwarappa, Supreeta R. Shettar, Mahadevaiah Neelambike Sumana, Vamshi P Dharan
article en
1 citations

Abstract

This case report highlights the management of recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) <i>Pseudomonas aeruginosa</i> in a post-renal transplant patient. Despite the challenges posed by antibiotic resistance, the patient was successfully treated with an extended infusion of meropenem, underscoring the efficacy of this approach in such difficult cases. The patient's recurrent infections required multiple hospitalizations and adjustments in treatment protocols, including the use of alternative antibiotics like fosfomycin and tailored immunosuppressive management to control both infection and rejection. This case is noteworthy for demonstrating the successful management of recurrent UTIs in the immunocompromised patient population, providing valuable insights into the treatment strategies that can be employed in similar clinical scenarios.

Frontiers in TransplantationVol. 4
JSS Academy of Higher Education and Research (IN), University of Florida (US), JSS Medical College and Hospital (IN)
JSS Academy of Higher Education and Research
Good health and well-being
Openalex Percentile: Top 18%
Urinary Tract Infections Management
1.35
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Case Report: Persistent drug-resistant Pseudomonas aeruginosa infection in a young post-kidney transplant patient that proved fatal — Ramakota Reddy, G. K. Megha, et al. · Frontiers in Transplantation (2025) | TGRS Research Map | TGRS