Asian consensus on normothermic intraperitoneal and systemic treatment for gastric cancer with peritoneal metastasis
Peritoneal metastasis (PM) is a major challenge in advanced gastric cancer (GC) with poor prognosis. Normothermic intraperitoneal and systemic treatment (NIPS) has become a promising therapeutic approach. This consensus aims to provide practical recommendations for NIPS treatment for gastric cancer with peritoneal metastasis (GCPM). The GRADE standards were used to rank evidence, and the Delphi method was employed for expert voting. 30 experts from China, Japan, South Korea, and Singapore participated in the development of this consensus. 28 experts participated in the voting process, which produced 29 statements covering diagnostic approaches, patient selection criteria, treatment regimens, management of intraperitoneal port placement, and conversion surgery considerations, and post-surgical treatment strategies in NIPS therapy. Based on current evidence and expert experience, these statements aim to improve the clinical outcomes of NIPS therapy for GCPM patients.
Authors
- Zhongyin Yang (ORCID: https://orcid.org/0000-0003-3595-9417)
- Wei Peng Yong (ORCID: https://orcid.org/0000-0003-4404-3777)
- Chao Yan (ORCID: https://orcid.org/0000-0002-3397-1992)
- Yanong Wang (ORCID: https://orcid.org/0000-0001-8454-2701)
- Dan Wu (ORCID: https://orcid.org/0000-0002-6661-2961)
- Kai Yin (ORCID: https://orcid.org/0000-0002-3351-4222)
- Yasuhiro Kodera (ORCID: https://orcid.org/0000-0002-6173-7474)
- Sheng Lu (ORCID: https://orcid.org/0000-0003-4637-4588)
- Hyung‐Ho Kim (ORCID: https://orcid.org/0000-0002-8916-0048)
- Joji Kitayama
- Ye Seob Jee (ORCID: https://orcid.org/0000-0003-3280-6351)
- Jiren Yu (ORCID: https://orcid.org/0000-0002-7904-107X)
- Zekuan Xu (ORCID: https://orcid.org/0000-0001-5179-4128)
- Xiangdong Cheng (ORCID: https://orcid.org/0000-0002-5099-490X)
- Jong‐Han Kim (ORCID: https://orcid.org/0000-0002-3862-8501)
- Hironori Yamaguchi (ORCID: https://orcid.org/0000-0002-8371-9410)
- Jimmy Bok Yan So (ORCID: https://orcid.org/0000-0002-9772-7905)
- Motohiro Imano (ORCID: https://orcid.org/0000-0003-2242-4245)
- Hironori Ishigami (ORCID: https://orcid.org/0000-0002-5027-9543)
- Won Jun Seo (ORCID: https://orcid.org/0000-0003-3447-7790)
- Jun Zhang
- Xiaowen Liu (ORCID: https://orcid.org/0000-0001-8397-0827)
- Han Liang (ORCID: https://orcid.org/0000-0003-0457-2877)
- Lin Chen (ORCID: https://orcid.org/0000-0002-3939-4305)
- Zhenggang Zhu
- Jian-Kun Hu
- Mingming Nie
- Yiping Mou
- Yutaka Yonemura
- Hui Cao (ORCID: https://orcid.org/0009-0005-0283-3289)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Seoul National University (KR)
- Jichi Medical University (JP)
- Bunkyo University (JP)
- National University of Singapore (SG)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Korea University (KR)
- Peking University (CN)
- Sichuan University (CN)
- Korea University Medical Center (KR)
- Renji Hospital (CN)
- Ruijin Hospital (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Seoul National University Bundang Hospital (KR)
- Fudan University Shanghai Cancer Center (CN)
- Zhejiang Cancer Hospital (CN)
- National University Cancer Institute, Singapore (SG)
- University of Tokyo Hospital (JP)
- Changhai Hospital (CN)
- Sichuan Cancer Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Peking University International Hospital (CN)
- Japan Society of Chemotherapy (JP)
- Kishiwada Tokushukai Hospital (JP)
- National University Hospital (SG)
- Shanghai Institute of Hematology (CN)
- Jichi Medical University Hospital (JP)
- Second Affiliated Hospital of Zhejiang University (CN)
- Hangzhou Medical College (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Dankook University Hospital (KR)
- Nagoya University (JP)
- The University of Tokyo (JP)
- Nanjing Medical University (CN)
- Kindai University (JP)
Publication Details
- Journal
- Gastric Cancer
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1007/s10120-025-01631-9
- Citations
- 3
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 6.02