Integrating anamnestic and lifestyle data with sphingolipid levels for risk-based prostate cancer screening
Circulating sphingolipids are promising biomarkers that, when combined with PSA, anamnestic, and lifestyle data, may enhance PCa screening precision and reduce the need for invasive, costly examinations.
Authors
- Giovanna Chiorino (ORCID: https://orcid.org/0000-0002-9502-6400)
- Andrea Zitella (ORCID: https://orcid.org/0000-0001-7331-2521)
- Maurizia Mello‐Grand (ORCID: https://orcid.org/0000-0003-1041-7590)
- Paola Ostano (ORCID: https://orcid.org/0000-0002-4000-2954)
- Francesca Ferranti (ORCID: https://orcid.org/0000-0002-4648-4069)
- S. Zaramella (ORCID: https://orcid.org/0000-0001-8482-3458)
- Amedeo Gagliardi (ORCID: https://orcid.org/0000-0001-9524-2130)
- Michele Dei (ORCID: https://orcid.org/0000-0001-7359-8558)
- Paolo Gontero (ORCID: https://orcid.org/0000-0002-9714-6596)
- Caterina Peraldo‐Neia (ORCID: https://orcid.org/0000-0002-5484-2030)
- Francesca Guana (ORCID: https://orcid.org/0000-0001-9358-5949)
- Luca Clivio (ORCID: https://orcid.org/0000-0002-5890-418X)
- Francesca Crivelli (ORCID: https://orcid.org/0000-0002-9880-8459)
- N. Testino (ORCID: https://orcid.org/0000-0002-5864-797X)
- Chiara Fiameni
- Marco Oderda (ORCID: https://orcid.org/0000-0003-4681-888X)
- Alessio Naccarati (ORCID: https://orcid.org/0000-0001-5774-0905)
- Rita Clara Paroni (ORCID: https://orcid.org/0000-0002-3186-8860)
- Alessandro Sinopoli (ORCID: https://orcid.org/0009-0009-2484-3495)
- Ilaria Gregnanin (ORCID: https://orcid.org/0000-0001-8810-8064)
- Francesca Montagnani (ORCID: https://orcid.org/0000-0002-2267-1337)
- M. Savioli (ORCID: https://orcid.org/0009-0004-7890-3864)
Institutions
- University of Milan (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale degli Infermi (IT)
- Ente Ospedaliero Cantonale (CH)
- Fondazione Ricerca Molinette (IT)
- Fondazione Edo ed Elvo Tempia (IT)
- Italian institute for Genomic Medicine (IT)
- Candiolo Cancer Institute (IT)
- Ospedale degli Infermi (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s12967-025-06820-9
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Fondazione CRT
- Compagnia di San Paolo
- Banca d'Italia
- Rete Oncologica del Piemonte e della Valle d'Aosta
- Ministero dell'Università e della Ricerca